Low Renin Hypertension - Is It a Stage of Essential Hypertension?
نویسندگان
چکیده
منابع مشابه
Low-renin and nonmodulating essential hypertension.
Low-renin hypertension (LREH) accounts for an important subset of the hypertensive human population and is associated with salt-sensitivity and diuretic response and is also common in black patients. An interesting finding in LREH is the presence of normal plasma aldosterone levels.1,2 The ratio of plasma aldosterone to renin activity is used to screen for adrenal adenomas and hyperplasia3 and ...
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The widespread clinical study of converting-enzyme inhibitors has shown that they are effective antihypertensive drugs even in patients who may manifest either normal or decreased plasma renin activity. This suggests either that renin in a site other than plasma may play a contributory role in essential hypertension or that the hypotensive effect is caused by increased concentrations of kinins ...
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Study of general haemodynamics in 15 patients with low-renin essential hypertension showed haemodynamic and pathophysiological heterogeneity. However, there was suppression of sympathetic nervous system function in all low-renin patients, regardless of haemodynamic pattern. Subnormal sympathetic nervous activity was manifested by a low normal mean plasma-noradrenaline concentration at rest, dim...
متن کاملIncreased plasma vasopressin in low renin essential hypertension.
Baseline plasma vasopressin concentrations were measured in 48 men (all 50 years old) with decreased plasma renin concentration and untreated, sustained essential hypertension and in 29 healthy normotensive men. Mean hypertensive plasma vasopressin concentration was more than twice as high as the corresponding normotensive level (15.7 +/- 2.2 [SE] vs 7.5 +/- 1.0 pg/ml; p less than 0.001). Plasm...
متن کاملMechanisms of suppression of renal kallikrein activity in low renin essential hypertension and renoparenchymal hypertension.
The mechanism of suppression of renal kallikrein activity in low renin essential hypertensive and renoparenchymal hypertensive patients was investigated in this study. From Sephadex G-200 column chromatography studies, a single kallikrein peak was observed in both kallikrein radioimmunoassay and kininogenase activity in all samples from normal subjects, low renin essential hypertensive and reno...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1977
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.121.347